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Shaping the future of biomanufacturing through chloroplast expression
Bright Biotech is a start-up pioneering the use of chloroplast-based protein expression systems to produce high-value proteins at scale. The company integrates recombinant genes into the chloroplast genome of plants to produce high-quality growth factors for research and emerging therapeutic applications. Dr Ahmad Sobri leads Bright Biotech’s protein extraction and purification efforts to ensure the quality of products, optimise downstream processes, and accelerate the research of the Manchester-based company.
Needs:
Reliable cold storage at +4 °C, -20 °C, -80 °C and -150 °C
Scalable cold storage and centrifugation options
Alarm systems for temperature monitoring
Sustainable, cost-effectivelab solutions
A full array of reliable cold storage
Bright Biotech needed to equip its new lab with a full suite of cold storage systems to
support its growing operations, including
fridges and standard, ultra-low temperature
(ULT) and cryogenic freezers, and a centrifuge.
The company chose to purchase from Haier
Biomedical because of its strong reputation for reliable, affordable and sustainable cooling solutions. Fridges and freezers – especially ULT and cryogenic freezers – are among the
most energy-intensive equipment in the lab,
so choosing models that are designed to be as efficient as possible can have a significant impact on the environment. Ahmad explained:
"Sustainability is one of our core values. Using chloroplasts for proteinexpression is not only efficient, but also environmentally friendly, and we aim to reflect that ethos in everything we do, including the suppliers we work with and equipment we buy. We chose Haier for its reputation in cooling, and found the equipment good value, energy efficient and dependable, which is idealfor a growing start-up like ours. These units are central to our workflows; they support everything from sample preparation to long-term storage. We use the +4 °C fridges for holding intermediate samples during purification,especially for overnight steps. The -20 °C freezers are for short-term storage of components – including DNA and PCR reagents – while the -80 °C units storepurified proteins, E. coli cells and plant material. The -150 °C freezer is used instead of liquid nitrogen for long-term storage of our production cell lines – it’s become a vital part of our set-up."
The Haier Biomedical equipment chosen by Bright Biotech has a number of practical features which are particularly useful to the lab, including the alarms and monitoring systems.
Bright Biotech’s work with chloroplast-based protein expression offers a sustainable alternative to traditional systems, supporting the production of high-value growth factors for use in areas such as wound healing and regenerative medicine. This focus on sustainability also shapes their operational choices, including the selection of energy-efficient cold storage solutions from HaierBiomedical. This equipment supports a range of workflows, from sample preparation to long-term storage, and features like built-in alarms have proven useful in day-to-day lab management. As the company continues to grow, this reliable infrastructure – and environmentally-conscious practices – will remain central to its approach.
